Beta-Lactam Antibiotics Semisynthetic Penicillins (part I) (A), MCQs for GPAT, NIPER, Drug inspector and Pharmacist - Gpatindia: Pharmacy Jobs, Admissions, Scholarships, Conference,Grants, Exam Alerts
Beta-Lactam Antibiotics Semisynthetic Penicillins (part I) (…
Oct 30, 2021
gpatindia.com
@arcusmedicine on Instagram: "Why clindamycin? Penicillin (or amoxicillin) is first-line therapy for streptococcal pharyngitis. However, in patients with a true penicillin allergy-especially IgE-mediated reactions like anaphylaxis or urticaria-beta-lactams should be avoided. Clindamycin is a guideline-supported alternative for Group A Streptococcus, offering reliable coverage without beta-lactam cross-reactivity. While macrolides are another option, resistance rates can vary, making clindamycin
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@arcusmedicine on Instagram: "Why clindamycin? Penicillin (or a…
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Instagramarcusmedicine
Beta-lactam antibiotics are a group of antibiotics that contain a beta-lactam ring as a common chemical feature. They disrupt the synthesis of the bacterial cell wall. Beta-lactam antibiotics inhibit bacterial cell wall synthesis. Due to the structural similarity to D-alanyl-D-alanine, beta-lactam antibiotics act as substrate analogues by covalently binding to the serine in the transpeptidase active site. In this way, they irreversibly block the enzyme that is essential for cell wall synthesis.
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